The article presents the chronology of the International Scientific and Practice Congress “Diabetes Mellitus, Its Complications and Surgical Infections” (November 19–21, 2019).

Today, the rapid and cost-effective treatment of patients with diabetic foot syndrome (DFS) is still challenging. The use of biomedical cell products (BCP) in this patients category has a clear pathogenetic orientation, but it remains not fully understood and generally accepted. The review presents the results of numerous studies confirming the efficacy of BCP for the treatment of predominantly superficial trophic defects in patients with neuropathic DFS. However, these technologies are still classified as adjuvant therapies. There are no clear algorithms and regulations for the use of BCP. It has been shown that their use accelerates the reparative processes in superficial trophic defects in patients with neuropathic DFS in combination with standard therapy and shortens the time of wound epithelialization. Considering the laboriousness and high cost of BCPs, the possibility of their use for the treatment of patients with neuroischemic form of DFS of various grades according to the WIfI classification should be considered.

The constant increase in the number of patients with diabetes mellitus, among whom the incidence of long-term non-healing wounds is many times higher than in the general population, requires constant analysis of treatment protocols and their correction, if necessary. The peculiarities of the wound healing process in the presence of diabetes mellitus include phase perversion and reduced reparative potential. Another problem is the infectious process taking place against the background of diabetes mellitus. Its features include a tendency towards chronicity, frequent persistence of resistant and multiresistive forms of bacteria, and the formation of biofilms. All these factors are pushing to search for new approaches to treatment, and one of the dynamically developing areas is additional treatment of wounds with various types of physical energies. On the one hand, the use of negative pressure, ultrasound, plasma flows, a pulsating jet of liquid, etc. of the wound healing process has been studied for several decades. At the same time, there are still many unanswered problems. One of them is the effectiveness of ultrasonic cavitation in the treatment of purulent-necrotic complications of the neuro-ischemic diabetic foot in the presence of biofilm forms of bacteria in the wound.

The article presents several clinical observations about the experience of treating Fournier's gangrene in a hospital in the Far North.

Surgical debridement is the gold standard in helping patients with purulent foci of any etiology and localization. The outcome and prognosis of treatment, as well as functional and cosmetic results, depend on the radicalism, thoroughness, and accuracy of this operation. Surgical debridement of the purulent focus is performed throughout the entire period of the existence of surgery and its underlying principles undergo minimal changes over time. However, at all specialized congresses and conferences, questions of terminology and nomenclature are always actively discussed in relation to this operation, and additional methods of physical, chemical, and mechanical effects on the wound are constantly being reported with the aim of cleansing and transferring it to the reparative stage. All these aspects require discussion, reflection and regular exchange of experience, in connection with which it was planned to hold this forum (the previous conference was held in May 2014, its materials can be found at: https://woundsurgery.ru/mezhdunarodnaya-nauchno -prakticheskaya-k-6 /).