Osteomyelitis agents of the long bones and their resistance
https://doi.org/10.17650/2408-9613-2016-3-2-24-30
Abstract
Objective: to study the dynamics of changes in the structure of osteomyelitis agents of the long bones and their sensitivity to germicide depending on the surgical treatment strategy.
Materials and methods. There were studied 1083 patterns of clinical material from 384 patients with different forms of the osteomyelitis of the long bones that were treated in a period from 2013 to 2015 in the Department of Wound and Wound Infections of A.V. Vishnevsky Institute of Surgery. The comparison group consisted of microbiological studies results of 115 similar patients who were on treatment for osteomyelitis in the same Department in 2010.
Results. The main osteomyelitis agents of the long bones both in the main and in the comparison group are representatives of the gram-positive coccal flora – S. aureus, S. epidermidis and in a less degree E. faecalis. Among gram-negative bacterium P. aeruginosa keeps the leading position. However, in the main group of patients it is noticed a significant reduction of leading pathogens resistance, and a detection of hospital re- and superinfection flora breakdown. Clinically, it is expressed by the fact that there were developed a surgical strategy of osteomyelitis of the long bones treatment of different etiology and localization in the Department of Wound and Wound Infections, which allow improving the results of treatment for such patients by reducing their length of stay in hospital and the possibility to avoid the infection of wounds by hospital strains of microorganisms.
About the Authors
R. P. Terekhova
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
V. A. Mitish
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia;
Russian Peoples Friendship University, Ministry of Education and Science of Russia
Russian Federation
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997;
6 Miklukho-Maklaya St., Moscow, 117198
Yu. S. Paskhalova
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia;
Russian Peoples Friendship University, Ministry of Education and Science of Russia
Russian Federation
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997;
6 Miklukho-Maklaya St., Moscow, 117198
G. E. Skladan
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
S. A. Prudnikova
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
L. A. Blatun
A.V. Vishnevsky Institute of Surgery, Ministry of Health of Russia
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
Russian Federation
27 Bol’shaya Serpukhovskaya St., Moscow, 117997
References
1. Зубков М.Н. Антибиотикопрофилактика и антибиотикотерапия гнойных осложнений в травматологии и ортопедии. Русский медицинский журнал 1999;1(7):15–9. [Zubkov M.N. Antibiotic prophylaxis and antibiotic treatment of purulent complications in traumatology and orthopedics. Russkiy meditsinskiy zhurnal = Russian Medical Journal 1999;1(7):15–9. (In Russ.)].
2. Шаповалов В.П., Овдеенко А.Г. Хирургическая инфекция при боевых повреждениях опорно-двигательного аппарата. Вестник хирургии им. И.И. Грекова 2004;1(2):60–8. [Shapovalov V.P., Ovdeenko A.G. Surgical infection of the musculoskeletal system combat injuries. Vestnik khirurgii im. I.I. Grekova = I.I. Grekov Bulletin of Surgery 2004;1(2):60–8. (In Russ.)].
3. Bowen T.R., Widmaier J.C. Host classification predicts infection after open fracture. Clin Orthop Relat Res 2005;(433):205–11. PMID: 15805959.
4. Абаев Ю.К., Адарченко А.А., Зафранская М.М. Гнойная хирургия детского возраста: меняющиеся перспективы. Детская хирургия 2004;(6):4–7. [Abaev Yu.K., Adarchenko A.A., Zafranskaya M.M. Purulent surgery of children’s age: the changing prospects. Detskaya khirurgiya = Pediatric Surgery 2004;(6):4–7. (In Russ.)].
5. Барская М.А., Кузьмин А.И., Куксов В.Ф. Хирургическая тактика при хроническом гематогенном остеомиелите у детей. Детская хирургия 2000;(4):31–2. [Barskaya M.A., Kuz’min A.I., Kuksov V.F. Surgical tactics in childhood chronic hematogenous osteomyelitis. Detskaya khirurgiya = Pediatric Surgery 2000;(4):31–2. (In Russ.)].
6. Ерюхин И.А., Гельфанд Б.Р., Шляпников С.А. Хирургические инфекции. Руководство. СПб.: Питер, 2003. С. 248–9. [Eryukhin I.A., Gel’fand B.R., Shlyapnikov S.A. Surgical infections. Guide. Saint Petersburg: Piter, 2003. Pp. 248–9. (In Russ.)].
7. Бактериологическая диагностика раневой инфекции. Методические рекомендации. Под ред. М.И. Кузина. М., 1984. [Bacteriological diagnostics of a wound fever. Methodical references. Ed. by M.I. Kuzin. Moscow, 1984. (In Russ.)].
8. Moultrie D., Hawker J., Cole S. Factors associated with multidrug-resistant Acinetobacter transmission: an integrative review of the literature. AORN J 2011;94(1):27–36. DOI: 10.1016/j.aorn.2010.12.026. PMID: 21722769.
9. Sheng W.H., Liao C.H., Lauderdale T.L. et al. A multicenter study of risk factors and outcome of hospitalized patients with infections due to carbapenem-resistant Acinetobacter baumannii. Int J Infect Dis 2010;14(9):e7649. DOI: 10.1016/j.ijid.2010.02.2254. PMID: 20646946.
Review
For citations:
Terekhova R.P., Mitish V.A., Paskhalova Yu.S., Skladan G.E., Prudnikova S.A., Blatun L.A. Osteomyelitis agents of the long bones and their resistance. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2016;3(2):24-30. (In Russ.) https://doi.org/10.17650/2408-9613-2016-3-2-24-30
Views:
745
Email this article 