COMPARATIVE ANALYSIS OF THE EFFICACY OF CURRENT DRESSINGS IN THE TREATMENT OF VENOUS TROPHIC ULCERS

of moist wounds in the treatment of patients with venous trophic ulcers.

Materials and methods. The results of treatment were analyzed in 67 patients aged 28 to 92 years (mean age 65.2 ± 7.2 years) who had 132 ulcers that had occurred in lower limb lymphatic and venous insufficiency.

Results. When salve dressings only were applied at all treatment stages, the healing rates for superficial ulcers were 0.78 cm² monthly and that for deep ones was 0.72 cm² monthly. When hydrocolloid dressings only were used in the granulations and epithelization phases, this indication was substantially higher (2.19 and 1.63 cm² monthly, respectively). When a native collagen membrane was implanted with simultaneous wound closure with hydrocolloid dressings, the mean healing rate for superficial ulcers was as large as 6.27 cm² monthly and that for deep ones was 1.79 cm² monthly, i.e. 2.5 times greater than that during traditional treatment. Overall, 2-week-to-8-month (mean, 2.4 months) treatment for trophic ulcers, by adhering to the principle of moist wound management, resulted in complete healing of 128 (97 %) of the 132 ulcers.

Conclusion. The application of the current dressings ensuring the management of moist wounds substantially accelerates wound defects resistant to traditional treatments. 

1. Белобородов В.Б. Современные принципы применения левофлоксацина в лечении инфекций кожи и мягких тканей. Consilium Medicum 2009;(1):38–42. [Beloborodov V.B. Actual issues of levofloxacine application for the treatment of skin and soft tissues’ infection. Consilium Medicum 2009;(1): 38–42. (In Russ.)].

2. Богомолов М.С., Слободянюк В.В. Лечение трофических язв различной этиологии. Вестник хирургии им. И.И. Грекова 2013;172(5):34–40. [Bogomolov М.S., Slobodyanyuk V.V. Treatment of trophic ulcers with different etiology. Vestnik khirurgii im. I.I. Grekova = I.I. Grekov Surgery Herald 2013;172(5):34–40. (In Russ.)].

3. Яковлев В.П., Блатун Л.А., Терехова Р.П. Клиническая эффективность нового комбинированного антимикробного препарата, содержащего ципрофлоксацин и тинидазол, при лечении больных с инфекциями кожи и мягких тканей. Антибиотики и химиотерапия 2005;50(2–3):48–51. [Yakovlev V.P., Blatun L.А., Теrekhovа R.P. Clinical efficiency of the new combined antimicrobial substance, containing ciprofloxacine and tinidazole, for the treatment of patients with skin and soft tissues’ infection. Antibiotiki i khimioterapiya = Antibiotics and Chemotherapy 2005;50(2–3):48–51. (In Russ.)].

4. Альбицкий А.В., Богачев В.Ю., Калинина Е.В. Лечение трофических язв венозной этиологии с точки зрения доказательной медицины. Ангиология и сосудистая хирургия 2006;12(2):137–45. [Аl’bitskiy А.V., Bogachev V.Yu., Kalinina Е.V. Treatment of trophic ulcers with venous etiology from the point of view of the evidence based medicine. Angiologiya i sosudistaya khirurgiya = Аngiology and Vascular Surgery 2006;12(2):137–45. (In Russ.)].