Innovations in the treatment of various etiologies wounds. Cold plasma wound treatment: a paradigm shift (literature review)
https://doi.org/10.25199/2408-9613-2026-13-2-16-22
Abstract
The aim of this study is to evaluate the results of scientific research on the use of cold plasma in various medical fields.
Early studies have provided evidence that plasma promotes wound healing through a beneficial combination of active substances and the modulation of inflammation in cells and tissues. Cold atmospheric plasma has been studied and clinically used to treat cancer, periodontitis, and other diseases, as it exerts cytotoxic, bactericidal, cell-proliferative, and anti-inflammatory effects on living tissues through the formation of reactive species. Thus, cold plasma is a versatile treatment for diseases associated with chronic inflammation and bacterial infections.
This review presents the most important biomedical applications of cold atmospheric or low-temperature plasma in modern medicine, demonstrating its effect on the healing of chronic and acute wounds.
About the Authors
I. Yu. Karpova
Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Irina Yu. Karpova – Ph.D. (Medicine), Professor, Head of the Department of Pediatric Surgery
10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005
S. L. Malinovskaya
Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Svetlana L. Malinovskaya – Ph.D. (Biology), Professor of the Department of Мedical Biophysics
10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005
D. I. Iydin
Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Dmitriy I. Iydin – Ph.D. (Physical and Mathematical Sciences), Ph.D. (Biology), Professor, Head of the Department of Мedical Biophysics
10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005
O. V. Drugova
Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Olga V. Drugova – Ph.D. (Biology), Associate Professor of the Department of Мedical Biophysics
10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005
G. S. Rozin
Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
German S. Rozin – 6th year student of the Pediatric Faculty
10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005
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Review
For citations:
Karpova I.Yu., Malinovskaya S.L., Iydin D.I., Drugova O.V., Rozin G.S. Innovations in the treatment of various etiologies wounds. Cold plasma wound treatment: a paradigm shift (literature review). Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2026;13(2):16-22. (In Russ.) https://doi.org/10.25199/2408-9613-2026-13-2-16-22
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