ririРаны и раневые инфекции. Журнал имени проф. Б.М. КостючёнкаWounds and wound infections. The prof. B.M. Kostyuchenok journal2408-96132500-0594Regional non-governmental organization “Surgical society - Wounds and wound infections”10.25199/2408-9613-2026-13-2-16-22riri-368Research ArticleОБЗОРЫ, ЛЕКЦИИ, ИСТОРИЯ РАН И РАНЕВЫХ ИНФЕКЦИЙREVIEWS, LECTURES, HISTORY OF WOUNDS AND WOUND INFECTIONSИнновации в лечении ран различной этиологии. Лечение ран холодной плазмой: смена парадигмы (обзор литературы)Innovations in the treatment of various etiologies wounds. Cold plasma wound treatment: a paradigm shift (literature review)https://orcid.org/0000-0002-7964-6132КарповаИ. Ю.KarpovaI. Yu.

Карпова Ирина Юрьевна – доктор медицинских наук, доцент, заведующий кафедрой детской хирургии

603005, Нижний Новгород, пл. Минина и Пожарского, д.10/1

Irina Yu. Karpova – Ph.D. (Medicine), Professor, Head of the Department of Pediatric Surgery

10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005

ikarpova73@mail.ruhttps://orcid.org/0000-0002-3744-9034МалиновскаяС. Л.MalinovskayaS. L.

Малиновская Светлана Львовна – доктор биологических наук, доцент, профессор кафедры медицинской биофизики

603005, Нижний Новгород, пл. Минина и Пожарского, д.10/1

Svetlana L. Malinovskaya – Ph.D. (Biology), Professor of the Department of Мedical Biophysics

10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005

https://orcid.org/0000-0002-8416-9377ИудинД. И.IydinD. I.

Иудин Дмитрий Игоревич – доктор биологических наук, доктор физико-математических наук, профессор, заведующий кафедрой медицинской биофизики

603005, Нижний Новгород, пл. Минина и Пожарского, д.10/1

Dmitriy I. Iydin – Ph.D. (Physical and Mathematical Sciences), Ph.D. (Biology), Professor, Head of the Department of Мedical Biophysics

10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005

https://orcid.org/0000-0001-7810-8191ДруговаО. В.DrugovaO. V.

Другова Ольга Валентиновна – кандидат биологических наук., доцент кафедры медицинской биофизики

603005, Нижний Новгород, пл. Минина и Пожарского, д.10/1

Olga V. Drugova – Ph.D. (Biology), Associate Professor of the Department of Мedical Biophysics

10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005

https://orcid.org/0009-0000-2378-175XРозинГ. С.RozinG. S.

Розин Герман Сергеевич – студент 6-го курса педиатрического факультета

603005, Нижний Новгород, пл. Минина и Пожарского, д.10/1

German S. Rozin – 6th year student of the Pediatric Faculty

10/1 Minin and Pozharsky Sq., Nizhniy Novgorod, 603005

ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава РоссииРоссияPrivolzhsky Research Medical University of the Ministry of Health of the Russian FederationRussian Federation2026170520261321622Copyright © Карпова И.Ю., Малиновская С.Л., Иудин Д.И., Другова О.В., Розин Г.С., 20262026Карпова И.Ю., Малиновская С.Л., Иудин Д.И., Другова О.В., Розин Г.С.Karpova I.Y., Malinovskaya S.L., Iydin D.I., Drugova O.V., Rozin G.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.riri.su/jour/article/view/368

Цель исследования – оценка результатов научных исследований по применению холодной плазмы в различных областях медицины.

Ранние исследования предоставили доказательства того, что плазма способствует заживлению ран благодаря полезному сочетанию активных веществ и модуляции воспаления в клетках и тканях. Холодную атмосферную плазму изучали и клинически применяли для лечения рака, пародонтита и других заболеваний, так как она оказывает цитотоксическое, бактерицидное, клеточно-пролиферативное и противовоспалительное действие на живые ткани путем образования реактивных частиц. Таким образом, холодная плазма является универсальным средством лечения заболеваний, связанных с хроническим воспалением и бактериальными инфекциями.

В данном обзоре представлены наиболее важные биомедицинские составляющие применения холодной атмосферной или низкотемпературной плазмы в современной медицине, демонстрирующие ее эффективность в заживлении хронических и острых ран.

The aim of this study is to evaluate the results of scientific research on the use of cold plasma in various medical fields.

Early studies have provided evidence that plasma promotes wound healing through a beneficial combination of active substances and the modulation of inflammation in cells and tissues. Cold atmospheric plasma has been studied and clinically used to treat cancer, periodontitis, and other diseases, as it exerts cytotoxic, bactericidal, cell-proliferative, and anti-inflammatory effects on living tissues through the formation of reactive species. Thus, cold plasma is a versatile treatment for diseases associated with chronic inflammation and bacterial infections.

This review presents the most important biomedical applications of cold atmospheric or low-temperature plasma in modern medicine, demonstrating its effect on the healing of chronic and acute wounds.

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The authors declare that there are no conflicts of interest present.