Modern dressings with enzymes for comprehensive management of various etiology wounds
https://doi.org/10.25199/2408-9613-2024-11-2-45-53
Abstract
The article is a review on the properties of modern Russian wound dressings containing long-acting enzymes immobilized on dialdehyde cellulose (oxidized cellulose). The authors present some clinical observations, as an example of their effective application.
Keywords
wounds,
wound infection,
purulent wound,
purulent-necrotic focus,
surgical infection,
local treatment,
enzyme preparations,
enzymes immobilized on oxidized cellulose
Supporting agencies: The study had no sponsorship
About the Authors
A. A. Ushakov
A. V. Vishnevsky National Medical Research Center of Surgery; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation
Russian Federation
Aleksandr A. Ushakov – MD, surgeon, head of the purulent department in Wounds and Wound Infections Unit; assistant at the department of plastic surgery
27 Bolshaya Serpukhovskaya Str., Moscow, 117997;
8 Miklukho-Maklaya Str., Moscow, 117198
V. A. Mitish
A. V. Vishnevsky National Medical Research Center of Surgery; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation
Russian Federation
Valery A. Mitish – MD, Cand. Sc. (Med.), Associate Professor, head of the department of wounds and wound infections; head of the department of disaster medicine
27 Bolshaya Serpukhovskaya Str., Moscow, 117997;
8 Miklukho-Maklaya Str., Moscow, 117198
Yu. S. Paskhalova
A. V. Vishnevsky National Medical Research Center of Surgery; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation
Russian Federation
Yulia S. Paskhalova – MD, Cand. Sc. (Med.), senior researcher at the department of wounds and wound infections; Associate Professor at the department of disaster medicine
27 Bolshaya Serpukhovskaya Str., Moscow, 117997;
8 Miklukho-Maklaya Str., Moscow, 117198
S. D. Magomedova
A. V. Vishnevsky National Medical Research Center of Surgery
Russian Federation
Russian Federation
Samera D. Magomedova – MD, purulent surgeon at the department of wounds and wound infections
27 Bolshaya Serpukhovskaya Str., Moscow, 117997
I. V. Borisov
A. V. Vishnevsky National Medical Research Center of Surgery; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation
Russian Federation
Igor V. Borisov – MD, Dr. Sc. (Med.), head of the diabetic foot office at Wounds and Wound Infections Department; Associate Professor at the department of disaster medicine
27 Bolshaya Serpukhovskaya Str., Moscow, 117997;
8 Miklukho-Maklaya Str., Moscow, 117198
S. А. Orudzheva
A. V. Vishnevsky National Medical Research Center of Surgery
Russian Federation
Russian Federation
Saida A. Orudhzeva – MD, Dr. Sc. (Med.), anesthesiologist-resuscitator, senior researcher at the department of wounds and wound infections
27 Bolshaya Serpukhovskaya Str., Moscow, 117997
References
1. Yencheva Yu. A. Efficiency of combined surgical treatment of third-degree burns = Yen’cheva Yu. A. Effektivnost’ kombinirovannogo khirurgicheskogo lecheniya ozhogov III stepeni: avtoref. dis. … kand. med. nauk. Perm’, 2017. (In Russ.)
2. Bensman V. M. Surgery of purulent-necrotic complications of the diabetic foot: a guide for doctors = Bensman V. M. Khirurgiya gnoyno-nekroticheskikh oslozhneniy diabeticheskoy stopy: rukovodstvo dlya vrachey. M., 2015. (In Russ.)
3. Galstyan G. R., Mitish V. A., Doronina L. P. The first experience of using the “Versajet” hydrosurgical system in patients with diabetes mellitus with long-term non-healing ulcerative defects of the feet = Galstyan G. R., Mitish V. A., Doronina L. P. Pervyy opyt ispol’zovaniya gidrokhirurgichnskoy sistemy “Versajet” u bol’nykh sakharnym diabetom s dlitel’no nezazhivayushchimi yazvennymi defektami stop. Endokrinnaya khirurgiya. 2008; 1 (2): 23–25. (In Russ.)
4. Bokeria L. A., Beloborodova N. V. Infection in cardiac surgery = Bokeriya L. A., Beloborodova N. V. Infektsiya v kardiokhirurgii. M., 2007. (In Russ.)
5. Vishnevsky A. A., Pechetov A. A., Golovteev V. V., et al. Re-osteosynthesis of the sternum using memory fixators after median sternotomy in conditions of chronic sternomediastinitis = Vishnevskiy A. A., Pechetov A. A., Golovteyev V. V. i dr. Reosteosintez grudiny s primeneniyem fiksatorov s effektom pamyati posle sredinnoy sternotomii v usloviyakh khronicheskogo sternomediastinita. Infektsii v khirurgii. 2009; 2 (7): 5–10. (In Russ.)
6. Vishnevskaya G. A. Chest wall plastic surgery in conditions of infected tissues = Vishnevskaya G. A. Plastika grudnoy stenki v usloviyakh infitsirovannykh tkaney: dis. … kand. med. nauk. M., 2005. (In Russ.)
7. Lednev P. V., Ran Yu. V., Belov Yu. V., et al. Postoperative sternomediastinitis = Lednev P. V., Ran Yu. V., Belov Yu. V. i dr. Posleoperatsionnyy sternomediastinit. Khirurgiya. 2018; 4: 84–89. (In Russ.)
8. Girgolav S. S. Gunshot wound = Girgolav S. S. Ognestrel’naya rana. L., 1956. S. 330. (In Russ.)
9. Glyantsev S. P. Dressings with proteolytic enzymes in the treatment of purulent wounds = Glyantsev S. P. Povyazki s proteoliticheskimi fermentami v lechenii gnoynykh ran. Khirurgiya. 1988; 12: 32–37. (In Russ.)
10. Gostishchev V. K. Enzyme therapy of non-specific surgical infection: author’s abstract = Gostishchev V. K. Enzimoterapiya nespetsificheskoy khirurgicheskoy infektsii: avtoref. dis. … dokt. med. nauk. M., 1972. (In Russ.)
11. Ivankov M. P., Kislenko A. M., Mishina L. V. Experience in using modern wound dressings with enzymes in the treatment of mine-explosive and gunshot wounds: advantages and disadvantages = Ivankov M. P., Kislenko A. M., Mishina L. V. Opyt primeneniya sovremennykh ranevykh pokrytiy s fermentami v lechenii minno-vzryvnykh i ognestrel’nykh raneniy: dostoinstva i nedostatki. V kn: 4-y Mezhdunarodnyy kongress “Rany i ranevyye infektsii” s konferentsiyey “Problemy anestezii i intensivnoy terapii ranevykh infektsiy”, 26–28 noyabrya 2018 g. M., 2018. S. 169–170. (In Russ.)
12. Kuzin M. I., Kostyuchenok B. M. Wounds and wound infection = Kuzin M. I., Kostyuchenok B. M. Rany i ranevaya infektsiya. M.: Meditsina, 1990. S. 90, 548, 554. (In Russ.)
13. Tolstykh M. P. Problems of complex treatment of purulent wounds of various genesis and trophic ulcers = Tolstykh M. P. Problema kompleksnogo lecheniya gnoynykh ran razlichnogo geneza i troficheskikh yazv: avtoref. dis. … dokt. med. nauk. M., 2002. (In Russ.)
14. Filatov V. N., Ryl’tsev V. V. Biologically active textile materials = Filatov V. N., Ryl’tsev V. V. Biologicheski aktivnyye tekstil’nyye materialy. M., 2002. (In Russ.)
15. Blatun L. A. Local drug treatment of wounds. Problems and new possibilities for their solution = Blatun L. A. Mestnoye medikamentoznoye lecheniye ran. Problemy i novyye vozmozhnosti ikh resheniya. Consilium Medicum. 2007; 9 (1): 1–16. (In Russ.)
16. Gostishchev V. K. General surgery = Gostishchev V. K. Obshchaya khirurgiya: monografiya. M.: Meditsina, 1997. (In Russ.)
17. Efimenko N. A. Polyenzyme preparations in purulent surgery = Yefimenko N. A. Polifermentnyye preparaty v gnoynoy khirurgii: metodicheskiye ukazaniya. M., 2005. 32 s. (In Russ.)
18. Pantireva Yu. M. Clinical surgery = Pantsyreva Yu. M. Klinicheskaya khirurgiya. M., 1988. 640 s. (In Russ.)
19. Adamyan A. A., Dobysh S. V., Kilimchuk L. E., et al. Biologically active dressings in the complex treatment of purulent-necrotic wounds = Adamyan A. A., Dobysh S. V., Kilimchuk L. Ye. i dr. Biologicheski aktivnyye perevyazochnyye sredstva v kompleksnom lechenii gnoynonekroticheskikh ran: metodicheskiye rekomendatsii. M., 2000. (In Russ.)
Review
For citations:
Ushakov A.A., Mitish V.A., Paskhalova Yu.S., Magomedova S.D., Borisov I.V., Orudzheva S.А. Modern dressings with enzymes for comprehensive management of various etiology wounds. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2024;11(2):45-53. (In Russ.) https://doi.org/10.25199/2408-9613-2024-11-2-45-53
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