A modern polymer based wound care coating for wound management
https://doi.org/10.25199/2408-9613-2023-10-2-24-31
Abstract
Pain management at phase 1 of the wound process includes wound cleaning due to the lysis of purulent-necrotic masses, control of the pathogenic microflora, and evacuation of wound discharge. These factors are achievable with a new composite depo-material having the textile base, hydrogel composition based on biopolysaccharide sodium alginate with immobilized active components – proteolytic enzyme of plant origin- papain and antimicrobial salt-like silver. Biosynthesis of silver nanoparticles and its presence in the composition in the cation form increases efficacy and eliminates toxicity of the treatment due to low silver concentration.
Supporting agencies: The work was done under Grant No 596ГРНТИ/63447 for conducting the scientific research.
About the Authors
E. O. Medusheva
COLETEX Limited Liability Company (COLETEX LLC)
Russian Federation
Russian Federation
Elena O. Medusheva – MD, Dr. Sc. (med), Deputy Director-General for innovations
21 Pavlovskaya Str., Moscow, 115093
Yu. S. Fidorovskaya
COLETEX Limited Liability Company (COLETEX LLC)
Russian Federation
Russian Federation
Yulia S. Fidorovskaya – Cand. Sc. (tech), researcher
21 Pavlovskaya Str., Moscow, 115093
M. A. Shchedrina
Federal State Budgetary Institution Burdenko Main Military Clinical Hospital of the Ministry of Defence of the Russian Federation (FSBI Burdenko Main Military Clinical Hospital of the Ministry of Defence of Russia)
Russian Federation
Russian Federation
Marina A. Shchedrina – MD, Cand. Sc. (med), senior researcher in the research laboratory (with vivarium), Research Center
3 Gospitalnaya Sq., Moscow, 105094
N. D. Oltarzhevskaya
COLETEX Limited Liability Company (COLETEX LLC)
Russian Federation
Russian Federation
Natalia D. Oltarzhevskaya – Dr. Sc. (tech), professor, Director General
21 Pavlovskaya Str., Moscow, 115093
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Review
For citations:
Medusheva E.O., Fidorovskaya Yu.S., Shchedrina M.A., Oltarzhevskaya N.D. A modern polymer based wound care coating for wound management. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2023;10(2):24-31. (In Russ.) https://doi.org/10.25199/2408-9613-2023-10-2-24-31
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