Use of triclosan-coated suture material as prevention of surgical site infections (literature review)
https://doi.org/10.25199/2408-9613-2021-8-2-28-32
Abstract
According to international data, the incidence of infections in the field of surgery in children and adults varies from 2.0 to 20.0 %. The occurrence of the above infections is influenced by many factors: the presence of comorbidities, ASA index, surgical wound class, NNIS risk index. Important factors include the quality of the suture. According to experts of the World Health Organization, 40.0–60.0 % of infections in the field of surgery can be prevented. The first microbiological study of suture (polyglactin 910) with triclosan was published in 2002. According to international studies, the use of a triclosan reduces the adhesion of bacteria to the suture, the viability of microbes and the release of inflammatory mediators. Triclosan actively prevents the colonization of the filament, in addition, concentrations sufficient to suppress the growth and reproduction of pathogens are maintained in the environment for a long time, resulting in the prevention of the development of infectious complications.
About the Authors
S. M. SharkovRussian Federation
1/9 4th Dobryninsky per., Moscow, 119049, Russia; 2/4 Bolshaya Pirogovskaya Str., Moscow, 119991, Russia
S. R. Ikhsanova
Russian Federation
2/4 Bolshaya Pirogovskaya Str., Moscow, 119991, Russia
References
1. Wang Z. X., Jiang C. P., Cao Y., Ding Y. T. Systematic review and meta-analysis of triclosan-coated sutures for the prevention of surgical-site infection = Wang Z. X., Jiang C. P., Cao Y., Ding Y. T. Sistematicheskiy i metaanaliz primeneniya shovnogo materiala s pokrytiyem iz triklozana dlya obzora infektsii oblasti khirurgicheskogo vmeshatel’stva. Kafedra travmatologii i ortopedii. 2013; 2 (6): 27–37. (In Russ.)
2. Bagnall N. M., Vig S., Trivedi P. Surgical-site infection. Surgery (Oxford). 2009; 27 (10): 426–430.
3. Malashenko A. A. Risk-oriented approach in the prevention of infections in the field of surgical intervention in pediatric surgery = Malashenko A. A. Riskooriyentirovannyy podkhod v profilaktike infektsiy v oblasti khirurgicheskogo vmeshatel’stva v detskoy khirurgii. Permskiy meditsinskiy zhurnal. 2017; 34 (4): 18–23. (In Russ.)
4. Odom-Forren J. Preventing surgical site infections. Nursing. 2006; 36 (6): 58–63.
5. Alexander J. W., Kaplan J. Z., Altemeier W. A. Role of suture materials in the development of wound infection. // Ann Surg. 1967; 165 (2): 192–199.
6. Katz S., Izhar M., Mirelman D. Bacterial adherence to surgical sutures. A possible factor in suture induced infection. Ann Surg. 1981; 194 (1): 35–41.
7. Leaper D., Assadian O., Hubner N.-O., et al. Antimicrobial sutures and prevention of surgical site infection: assessment of the safety of the antiseptic triclosan. Int Wound J. 2011; 8 (6): 556–566.
8. Leaper D., Wilson P., Assadian O., et al. The role of antimicrobial sutures in preventing surgical site infection. Ann R Coll Surg Engl. 2017; 99 (6): 439–443.
9. Bhargava H. N., Leonard P. A. Triclosan: Applications and safety. Am J Infect Control. 1996; 24 (3); 209–218.
10. Davison J., Maillard J.-Y., Pagès J.-M. et al. Opinion on triclosan – antimicrobial resistance. Scientific Committee on Consumer Safety. SCCP/1251/09. 22 June 2010.
11. Itani K. M., Wilson S. E., Awad S. S., et al. Ertapenem versus cefotetan prophylaxis in elective colorectal surgery. New Engl J Med. 2006; 355 (25): 2640–2651.
12. Elek S. D., Conen P. E. The virulence of Staphylococcus pyogenes for man; a study of the problems of wound infection. Br J Exp Pathol.1957; 38 (6): 573–586.
13. Rothenburger S., Spangler D., Bhende S., et al. In Vitro antimicrobial evaluation of coated Vycryl Plus antibacterial suture (cjated Polyglactin 910 with Triclosan) using zone of inhibition assays. Surg Infect (Larchmt). 2002; 3 Suppl 1(sl): S79–87
14. Storch M. l., Rothenburger S. J., Jacinto G. Experimental efficacy study of coated Vicryl* Plus antibacterial suture in guinea pigs challenged with Staphylococcus aureus. Surg Infect (Larchmt). 2004; 5 (3): 281–288.
15. Edmiston C. E., Seabrook G. R., Goheen M. P., et al. Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination. J Am Coll Surg. 2006; 203 (4): 481–489.
16. Rozzelle C. J., Leonardo J., Li V. Antimicrobial suture wound closure for cerebrospinal fluid shunt surgery: a prospective, double-blinded, randomized controlled trial. J Neurosurg Pediatr. 2008; 2 (2): 111–117.
17. Galal I., El-Hindawy K. Impact of using triclosan antibacterial sutures on incidence of surgical site infection. Am J Surg. 2011; 202 (2): 133–138.
18. Rasić Z., Schwarz D., Adam V. N., et al. Efficacy of antimicrobial triclosancoated polyglactin 910 (Vicryl* Plus) suture for closure of the abdominal wall after colorectal surgery. Coll Antropol. 2011; 35 (2): 439–443.
19. Baracs J., Huszár O., Sajjadi S. G., Horváth O. P. Surgical site infections after abdominal closure in colorectal surgery using triclosan-coated absorbable suture (PDS Plus) vs. uncoated sutures (PDS II): a randomized multicenter study. Surg Infect. 2011; 12 (06): 483–489.
20. Zhang Z. T., Zhang H. W., Fang X. D., et al. Cosmetic outcome and surgical site infection rates of antibacterial absorbable (polyglactin 910) suture compared to Chinese silk suture in breast cancer surgery: a randomized pilot research. Chin Med J (Engl). 2011; 124 (5): 719–724.
21. Seim B. E., Tønnessen T., Woldbaek P. R. Triclosan-coated sutures do not reduce leg wound infections afer coronary artery bypass grafting. Interact Cardiovasc Thorac Surg. 2012; 15 (3): 411–415.
22. Turtiainen J., Saimanen E. I., Mäkinen K.T., et al. Effect of triclosan-coated sutures on the incidence of surgical wound infection afer lower limb revascularization surgery: a randomized controlled trial. World J Surg. 2012; 36 (10): 2528–2534.
23. Singh H., Emmert M. Y., Sakaguchi H., et al. Antibacterial suture reduces surgical site infections in coronary artery bypass grafting. Heart Surg Forum. 2010; 13: S85.
24. Khachatryan N., Dibirov M., Omelyanovsky V., et al. Prevention of postoperative infections in abdominal surgery using reabsorbable suture with antibacterial activity (Vicryl Plus) versus reabsorbable standard sutures. Surg Infect (Larchmt). 2011; 12: 13–14.
25. Mattavelli I., Nespoli l., Alferi S., et al. Triclosan-coated suture to reduce surgical site infection after colorectal surgery. Surg Infect. 2011; 12: 14–15.
26. Williams N., Sweetland H., Goyal S., et al. Randomized trial of antimicrobialcoated sutures to prevent surgical site infection afer breast cancer surgery. Surg Infect (Larchmt). 2011; 12 (6), p. 469–474.
27. Isik I., Selimen D., Senay S., Alhan C. Efciency of antibacterial suture material in cardiac surgery: a doubleblind randomized prospective study. Heart Surg Forum. 2012; 15 (1): E40–E45.
28. Justinger C., Moussavian M.R., Schlueter C., et al. Antibacterial [corrected] coating of abdominal closure sutures and wound infection. Surgery. 2009; 145 (3): 330–334.
29. Picó R. B., Jiménez L. A., Sánchez M. C., et al. Prospective study comparing the incidence of wound infection following appendectomy for acute appendicitis in children: conventional treatment versus using reabsorbable antibacterial sutures or gentamicin-impregnated collagen fleeces. Cir Pediatr. 2008; 21 (4): 199–202.
30. Fleck T., Moidl R., Blacky A., et al. Triclosan-coated sutures for reduction of sterna wound infections: economic considerations. Ann Thorac Surg. 2007; 84 (1): 232–236.
Review
For citations:
Sharkov S.M., Ikhsanova S.R. Use of triclosan-coated suture material as prevention of surgical site infections (literature review). Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2021;8(2):28-32. (In Russ.) https://doi.org/10.25199/2408-9613-2021-8-2-28-32