Using wound size digital monitoring to check the treatment effectiveness on the example of the analysis of the diabetes’ influence on the trophic ulcers healing dynamics in patients with lower extremities venous insufficiency

Objective: comparative analysis of the diabetes mellitus impact on the speed of lower extremities long-existing soft tissue defects healing in patients with chronic venous insufficiency.

Materials and methods. In a retrospective comparative study were included 52 patients without hemodynamically significant lesions of the arteries and with lower extremities veins pathology confirmed by ultrasound who had 95 ulcers (C6 class of CEAP) sized from 1 to 10 cm2.

Results. The average period of superficial ulcers healing until complete epithelialization of the wound surface in patients without diabetes mellitus was 1.1 months, and in the presence of diabetes mellitus it was 0.9 months. Average speed of the healing of such ulcers treated with application of hydrocolloid dressings in patients without diabetes mellitus was 4.7 cm2/month, and patients with diabetes mellitus – 2.6 cm2/month. The average period of healing the deep ulcers in patients without diabetes mellitus (2.6 months) and in patients with diabetes mellitus (2.4 month) also did not significantly differ. At the same time, the average speed of healing the deep ulcers treated with application of hydrocolloid dressings in patients without diabetes mellitus was 1.4 cm2/month, and in patients with diabetes mellitus – 1.3 cm2/month. In cases of treatment with implantation of collagen membranes these parameters were 1.8 and 1.2 cm2/month, respectively.

Conclusions. The speed of "venous" trophic ulcers healing in patients without diabetes mellitus was slightly higher than in patients with diabetes mellitus, but significant difference in the speed of wound healing between these two patient groups was observed only in cases when native collagen membranes were used for deep ulcers treatment of.

1. Privol’nev V. V., Paskhalova Yu. S., Rodin A. V., Mitish V. A. Local treatment for wounds and wound infection according to the results of an anonymous survey of surgeons in Russia. Wounds and Wound Infections = Rany` i ranevy`e infekcii. Zhurnal imeni prof. B.M. Kostyuchyonka. 2016; 3 (1): 19-24 (In Russ.).

2. Bogomolov M. S., Bogomolova V. V. Evaluation of the effectiveness of treatment of trophic ulcers using modern digital technologies. Materials of the International scientific-practical conference "Surgical infections of skin and soft tissues in children and adults". Simferopol, 2017: 34-36.

3. Golub A. V., V.V. Privolnev V. V. Topical antibacterial therapy for surgical skin and soft tissue infections in outpatient settings: summands of success. Wounds and Wound Infections = Rany` i ranevy`e infekcii. Zhurnal imeni prof. B.M. Kostyuchyonka. 2014; 1 (1): 33–37 (In Russ.).

4. Bogdanets L. I., Smirnova E. S., Vasiliev Efficiveness of Dioxidine in the treatment of trophic ulcers of venous etiology. Pirogov Russian Journal of Surgery = Khirurgiya. Zhurnal imeni N. I. Pirogova. 2014; 9: 64–67 (In Russ.).

5. Sood A., Granick M. S., Tomaselli N. L. Wound Dressings and Comparative Effectiveness Data. Advances in wound care. 2014; 3 (8): 511–529.