Review of local medicines, used in the treatment of diabetic foot syndrome with purulo-necrotic complications

The article provides  an overview of local medicines used in wounds’ treatment  for patients with purulo-necrotic complications of diabetic foot syndrome (DFS) and the requirements  for these preparations  at the present-day stage of wound healing process development and also the principles of monitoring  of  wounds of different etiology. The above material also allows you to get acquainted with the classification of local medicines groups, their brief characteristics with highlighting the peculiarity of each group, strengths and weaknesses, indications, contraindications and possible mistakes of their using. Here is given the detailed description of  main groups modern wound coverings based on alginates, hydrocolloids, hydrogels and histo-equivalent-bioplastic material of hyaluronic acid. There were made conclusions about the lack of information on the real clinical effectiveness of modern dressings and about  numerous and not systematic approaches for measuring the course of the wound healing process using various biological models. This explains the urgency to improving the modern diagnostic algorithm for measuring the course of the wound healing process and the need to develop an universal model that allows to identify its peculiarities and regularities, including efficiency assessment for local treatment of DFS purulo-necrotic complications.

wounds, wound process, local medicines, wound coverings, alginates, hydrocolloids, hydrogels, hyaluronic acid, histoequivalentbioplastic material, diabetic foot syndrome, purulo-necrotic complications, diabetes mellitus

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