Surgical treatment of wound defects in fulminant purpura
https://doi.org/10.17650/2408-9613-2017-4-2-24-33
Abstract
Fulminant purpura (FP) is an acute rapidly progressing syndrome of disseminated intravascular coagulation, it is accompanied by specific skin manifestations and characterized by extremely high lethality in the absence of adequate timely treatment. This multicomponent disease requires a multidisciplinary approach to its treatment and the phasing of surgical interventions. We have accumulated experience in successful treatment of three patients with fulminant purpura of different etiologies from 2014 to the present time. This article provides an example of the complex treatment of a three-year-old girl with fulminant purpura of both hips that was connected with the deficiency of protein C and the expression after acute respiratory illness.
About the Authors
I. E. KoltunovRussian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
R. A. Keshishyan
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
M. A. Petrov
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
N. S. Shlyapnikova
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
R. A. Baranov
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
I. V. Pankratov
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
D. D. Pavlova
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
P. V. Svirin
Russian Federation
Department of pediatric surgery
1/9, Dobryninsky lane 4th, Moscow, 119049
References
1. Rumyantsev A. G., Maschan A. A., Zharkov P. A., Svirin P. V. Federal clinical recommendations on diagnosis, prevention and treatment of thrombosis in children and National Society of Children Hematologists, oncologists of the Ministry of Health of Russia (In Russ.).
2. Davis M. D., Dy K. M., Nelson S. Presentation and outcome of purpura fulminans associated with peripheral gangrene in 12 patients at Mayo Clinic. J Am Acad Dermatol. 2007; 57(6): 944–56.
3. Edlich R. F. et al. Modern concepts of the diagnosis and treatment of purpura fulminans. J Environ Pathol Toxicol Oncol. 2008; 27(3): 191–196.
4. Chalmers E. et al. Purpura fulminans: recognition, diagnosis and management. Arch Dis Child. 2011; 96(11): 1066–1071.
5. Betrosian A. P., Berlet T., Agarwal B. Purpura fulminans in sepsis. Am J Med Sci. 2006; 332(6): 339–345.
6. Fitzgerald C. J. et al. Purpura fulminans caused by community-associated methicillin-resistant Staphylococcus aureus. Am J Emerg Med. 2012; 30(6): 1013.
7. Defining the group A streptococcal toxic shock syndrome. Rationale and consensus definition. The Working Group on Severe Streptococcal Infections. JAMA. 1993 Jan 20; 269(3): 390–391.
8. Edlich R.F. et al., Massive soft tissue infections: necrotizing fasciitis and purpura fulminans. J Long Term Eff Med Implants. 2005; 15(1): 57–65.
Review
For citations:
Koltunov I.E., Keshishyan R.A., Petrov M.A., Shlyapnikova N.S., Baranov R.A., Pankratov I.V., Pavlova D.D., Svirin P.V. Surgical treatment of wound defects in fulminant purpura. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2017;4(2):24-32. (In Russ.) https://doi.org/10.17650/2408-9613-2017-4-2-24-33