Hyperbaric oxygenation in treatment of wound infections
https://doi.org/10.17650/2408-9613-2016-3-3-20-25
Abstract
Wound infection is one of the most frequent indications for using the method of hyperbaric oxygenation (HBO) in surgical practice. The effects of HBO are not always explainable from the point of general ideas about the "super-delivery" of oxygen. During the HBO it is modified a synthesis of a number of biologically active substances and can be noted persistent changes in various biochemical processes. Periodic increases of oxygen partial pressure (pO2 ) in damaged tissues afford evident effect on the dynamics of the wound process. Active forms of oxygen and nitrogen play the role of signaling molecules during the start of cascades of biochemical reactions leading to the synthesis of growth factors, cytokines and other hormonally active substances which are involved in wound healing.
About the Authors
E. Ja. Kolchina
Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia
Russian Federation
Department of hyperbaric oxygenation
Russian Federation
Department of hyperbaric oxygenation
V. G. Bagaev
Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia;
Research Institute of Emergency Pediatric Surgery and Traumatology, Moscow Healthcare Department
Russian Federation
Russian Federation
R. T. Nalbandjan
Research Institute of Emergency Pediatric Surgery and Traumatology, Moscow Healthcare Department
Russian Federation
Russian Federation
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Review
For citations:
Kolchina E.J., Bagaev V.G., Nalbandjan R.T. Hyperbaric oxygenation in treatment of wound infections. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2016;3(3):20-25. (In Russ.) https://doi.org/10.17650/2408-9613-2016-3-3-20-25
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