Внедрение концепции раневого баланса: результаты и рекомендации на будущее
Аннотация
Опубликовано:
Global Wound Care Journal & Wounds International Кэннон-стрит, 108
Лондон EC4N 6EU, Соединенное Королевство (108 Cannon Street, London EC4N 6EU, UK) Тел.: + 44 (0)20 3735 8244
Список литературы
1. Ahmajärvi K, Isoherranen K, Venermo M (2022) Cohort study of diagnostic delay in the clinical pathway of patients with chronic wounds in the primary care setting. BMJ Open 12(11): e062673
2. Alnaser F (2020) Effective communication skills and patient’s health. CPQ Neurol Psychol 3(4): 1-11
3. Anghel EL, DeFazio MV, Barker JC et al (2016) Current Concepts in Debridement: Science and Strategies. Plast Reconstr Surg 138(3 Suppl): 82S-93S
4. Armstrong DG, Jude EB (2002) The role of matrix metalloproteinases in wound healing. J American Pod Med Assn 92(1): 12-8
5. Atkin L, Bućko Z, Conde Montero E et al (2019) Implementing TIMERS: the race against hard-toheal wounds. J Wound Care 23(Sup3a): S1-50
6. Atkin L, Barrett S, Chadwick P et al (2020) Evaluation of a superabsorbent wound dressing, patient and clinician perspective: a case series. J Wound Care 29(3): 174-82
7. Avishai E, Yeghiazaryan K, Golubnitschaja O (2017) Impaired wound healing: facts and hypotheses for multi-professional considerations in predictive, preventive and personalised medicine. EPMA J 8(1): 23-33
8. Ayavoo T, Murugesan K and Gnanasekaran A (2021) Roles and mechanisms of stem cell in wound healing. Stem Cell Investig 8: 4
9. Ball C, Taylor C, Salgado B et al (2025) In vitro evaluation of the capability of a silicone superabsorbent polymer (SAP) dressing to modulate pro-inflammatory cytokines. Wounds Int 16(2): 12-23
10. Bhattad PB, Pacifico L (2022) Empowering Patients: Promoting Patient Education and Health Literacy. Cureus 14(7): e27336
11. Blome C, Baade K, Debus ES et al (2014) The “Wound-QoL”: a short questionnaire measuring quality of life in patients with chronic wounds based on three established disease-specific instruments. Wound Repair Regen 22(4): 504-14
12. Blome C, Candas E, Erfert-Berge C et al (2024) Implementing the Wound Balance concept into routine practice worldwide. Wounds Int 15(2): 44-50
13. Boniol M, Kunjumen T, Nair TS et al (2022) The global health workforce stock and distribution in 2020 and 2030: a threat to equity and ‘universal’ health coverage? BMJ Glob Health 7(6): e009316
14. Buchstein N, Hoffmann D, Smola H et al (2009) Alternative proteolytic processing of hepatocyte growth factor during wound repair. Am J Pathol 174(6): 2116-28
15. Candas E, Forster J, Schäfer J et al (2021) HydroClean® Made Easy. Wounds International
16. Carter MJ, DaVanzo J, Haught R et al (2023) Chronic wound prevalence and the associated cost of treatment in Medicare beneficiaries: Changes between 2014 and 2019. J Med Econ 26(1): 894-901
17. Choo J, Nixon J, Nelson A (2019) Autolytic debridement for pressure ulcers. Cochrane Database Syst Rev 2019(6): CD011331
18. Cullen B, Gefen A (2023) The biological and physiological impact of the performance of wound dressings. Int Wound J 20(4): 1292-303
19. Dissemond J, Protz K, Erfurt-Berge C et al (2022a) Wundbehandlung ohne kurative Zielsetzung: Ein Positionspapier der Initiative Chronische Wunden (ICW) e. V [Wound treatment without curative intention: position paper of the Initiative Chronische Wunden (ICW) e. V.]. Dermatologie (Heidelb) 73(7): 550-5
20. Dissemond J, Malone M, Ryan H et al (2022b) Implementation of the M.O.I.S.T. concept for the local treatment of chronic wounds into clinical practice. Wounds International 13(4): 34–43
21. Eming SA, Koch M, Krieger A, et al (2010) Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds. J Proteome Res 9(9): 4758-66
22. Erfurt-Berge C, Michler M, Renner R (2021) Versorgungszustand von Patienten vor Zuweisung an ein universitäres Wundzentrum [Standard of patient-centred care before admission to a university wound centre]. Hautarzt 72(6): 517-24
23. Eriksson E, Liu PY, Schultz GS et al (2022) Chronic wounds: Treatment consensus. Wound Repair Regen 30(2): 156-71
24. Fletcher J, Edmonds M, Madden J et al (2024) Demystifying infection in the diabetic foot. Wounds UK
25. Gao M, Guo H, Dong X et al (2024) Regulation of inflammation during wound healing: the function of mesenchymal stem cells and strategies for therapeutic enhancement. Front Pharmacol 15: 1345779
26. Gefen A, Alves P, Beeckman D et al (2024) How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs. Adv Wound Care (New Rochelle) 13(1): 34-52
27. Giguère A, Zomahoun HTV, Carmichael PH et al (2020) Printed educational materials: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev 8(8): CD004398
28. Gould L, Abadir P, Brem H et al (2015) Chronic wound repair and healing in older adults: current status and future research. J Am Geriatr Soc 63(3): 427-38
29. Guest JF, Fuller GW, Vowden P (2020) Cohort study evaluating the burden of wounds to the UK’s National Health Service in 2017/2018: update from 2012/2013. BMJ Open 10: e045253
30. Herrick S, Ashcroft G, Ireland G et al (1997) Upregulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation. Lab Invest 77(3): 281-8
31. Holm A, Karlsson V, Dreyer P (2021) Nurses’ experiences of serving as a communication guide and supporting the implementation of a communication intervention in the intensive care unit. Int J Qualitative Stud Health Wellbeing 16(1): 1971598
32. House of Lords Hansard (2021) Written Statements and Written Answers Session 2019-21, No. 175 21 January 2021. Available at: https://hansard.parliament.uk/commons/2021-01-21 (accessed 05.02.2025)
33. Janke TM, Kozon V, Valiukeviciene S et al (2024) Assessing health-related quality of life using the Wound-QoL-17 and the Wound-QoL-14-Results of the cross-sectional European HAQOL study using item response theory. Int Wound J 21(8): e70009
34. Kandhwal M, Behl T, Singh S et al (2022) Role of matrix metalloproteinase in wound healing. Am J Transl Res 14(7): 4391-405
35. Kapp S, Santamaria N (2017) The financial and quality-of-life cost to patients living with a chronic wound in the community. Int Wound J 14(6): 1108-19
36. Khalid KA, Nawi AFM, Zulkifli N et al (2022) Aging and Wound Healing of the Skin: A Review of Clinical and Pathophysiological Hallmarks. Life (Basel) 12(12): 2142
37. King A, Hoppe RB (2013) “Best practice” for patientcentered communication: a narrative review. J Grad Med Educ 5(3): 385-93
38. Krzyszczyk P, Schloss R, Palmer A, Berthiaume F (2018) The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Prowound Healing Phenotypes. Front Physiol 9: 419
39. Langemo D, Faan RN, Campbell K et al (2021) Applying Frailty Syndrome to the Skin: A Review and Guide for Prevention and Management. Adv Skin Wound Care 34(8): 444-7
40. Lauer G, Sollberg S, Cole M et al (2000) Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds. J Invest Dermatol 115(1): 12-8
41. LeBlanc K, Woo K (2022) A pragmatic randomised controlled clinical study to evaluate the use of silicone dressings for the treatment of skin tears. Int Wound J 19(1): 125-34
42. Lindholm C, Searle R (2016) Wound management for the 21st century: combining effectiveness and efficiency. Int Wound J 2(Suppl 2): 5-15
43. Lindley LE, Stojadinovic O, Pastar I (2016) Biology and Biomarkers for Wound Healing. Plast Reconstr Surg 138(3 Suppl): 18S-28S
44. Lumbers M (2019) TIMERS: undertaking wound assessment in the community. Br J Community Nurs 24(Sup12): S22-S25
45. Mamun AA, Shao C, Geng P (2024) Recent advances in molecular mechanisms of skin wound healing and its treatments. Front Immunol 15: 1395479
46. Mayer DO, Tettelbach WH, Ciprandi G et al (2024) Best practice for wound debridement. J Wound Care 33(Sup6b): S1-32
47. Mikosiński J, Kalogeropoulos K, Bundgaard L (2022) Longitudinal Evaluation of Biomarkers in Wound Fluids from Venous Leg Ulcers and Split-thickness Skin Graft Donor Site Wounds Treated with a Protease-modulating Wound Dressing. Acta Derm Venereol 102: adv00834
48. National Library of Medicine (2022) Chronic wounds: Learn More – What are the treatment options for chronic wounds? Available at: https://www.ncbi.nlm.nih.gov/books/NBK326436/ (accessed 257.01.2025)
49. National Library of Medicine (2023a) Wound physiology. Available at: https://www.ncbi.nlm.nih.gov/books/NBK518964/ (accessed 10.01.2025)
50. National Library of Medicine (2023b) Wound dehiscence. Available at: https://www.ncbi. nlm.nih.gov/books/NBK551712/#:~:text=The%20causes%20of%20dehiscence%20are,or%20drainage%20at%20the%20site. (accessed 04.02.2025)
51. National Library of Medicine (2023c) Wound debridement. Available at: https://www.ncbi.nlm.nih.gov/books/NBK507882/#:~:text=Debridement%20for%20most%20wounds%20is,stimulating%20activity%20of%20growt (accessed 04.02.2025)
52. National Library of Medicine (2025) Wound Assessment. Available at: https://pubmed.ncbi.nlm.nih.gov/29489199/ (accessed 27.01.2025)
53. National Institute for Health and Care Excellence (2024) Leg ulcer – venous. Available at: https://cks.nice.org.uk/topics/leg-ulcervenous/#:~:text=A%20venous%20leg%20ulcer%20occurs,ankle%20to%20mid%2Dcalf) (accessed 27.01.2025)
54. Nwomeh BC, Yager DR, Cohen IK (1998) Physiology of the chronic wound. Clin Plastic Surgery 25(3): 341-56
55. Olsson M, Järbrink K, Divakar U et al (2019) The humanistic and economic burden of chronic wounds: a systematic review. Wound Repair Regen 27(1): 114-125
56. Ousey K, Rogers AA, Rippon MG (2016) HydroClean® plus: a new perspective to wound cleansing and debridement. Wounds UK 12(1): 78-87
57. Pađen L, Gschwind G, Vettorazzi R (2024) Facilitators and barriers for nurses when educating people with chronic wounds - A qualitative interview study. J Tissue Viability 33(2): 174-78
58. Patel S, Maheshwari A, Chandra A (2016) Biomarkers for wound healing and their evaluation. J Wound Care 25(1): 46-55
59. Probst A (2019) Zetuvit Plus Silicone Border Made Easy. Wounds International
60. Queen D, Harding K (2023) What’s the true costs of wounds faced by different healthcare systems around the world? Int Wound J 20(10): 393538
61. Raziyeva K, Kim Y, Zharkinbekov Z, Kassymbek K (2021) Immunology of Acute and Chronic Wound Healing. Biomolecules 11(5): 700
62. Sawaya AP, Stone RC, Brooks SR (2020) Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing. Nat Commun 11(1): 4678
63. Schilrreff P, Alexiev U (2022) Chronic Inflammation in Non-Healing Skin Wounds and Promising Natural Bioactive Compounds Treatment. Int J Mol Sci 23(9): 4928
64. Sen CK (2023) Human Wound and Its Burden: Updated 2022 Compendium of Estimates. Adv Wound Care 12: 657-70
65. Sharkiya SH (2023) Quality communication can improve patient-centred health outcomes among older patients: a rapid review. BMC Health Serv Res 23(1): 886
66. Shi C, Wang C, Liu H et al (2020) Selection of Appropriate Wound Dressing for Various Wounds. Front Bioeng Biotechnol 8: 182
67. Sibbald RG, Elliott JA, Persaud-Jaimangal R (2021) Wound Bed Preparation. Adv Skin Wound Care 34(4): 183-95
68. Stacey MC, Phillips SA, Farrokhyar F (2019) Evaluation of wound fluid biomarkers to determine healing in adults with venous leg ulcers: a prospective study. Wound Repair Regen 27(5): 509-18
69. Swoboda L. Multi-layer silicone SAP dressing for wound prophylaxis. Presented at Symposium on Advanced Wound Care (poster EBP-018) Las Vegas, Nevada, 2-5 October 2024
70. Tickle J (2013) Living day-to-day with a heavily exuding wound: Recommendations for practice. Wounds UK 8(1):77-78
71. Trengove NJ, Bielefeldt-Ohmann H, Stacey MC (2000) Mitogenic activity and cytokine levels in nonhealing and healing chronic leg ulcers. Wound Repair Regen 8(1): 13-25
72. Trouth S (2024) Introducing Wound Balance: placing the patient at the heart of wound healing. Wounds UK 20(1): 32-7
73. Ulrich D, Lichtenegger F, Unglaub F et al (2005) Effect of chronic wound exudates and MMP-2/9 inhibitor on angiogenesis in vitro. Reconstr Surg 116(2): 539-45
74. von Stülpnagel CC, da Silva N, Augustin M et al (2021) Assessing the quality of life of people with chronic wounds by using the cross-culturally valid and revised Wound-QoL questionnaire. Wound Repair Regen 29(3): 452-59
75. Veličković VM, Chadwick P, Rippon MG (2020) Cost-effectiveness of superabsorbent wound dressing versus standard of care in patients with moderate-to-highly exuding leg ulcers. J Wound Care 29(4): 235-46
76. Veličković VM, Prieto PA (2022) Superabsorbent wound dressings versus foams dressings for the management of moderate-to-highly exuding venous leg ulcers in French settings: An early stage model-based economic evaluation. J Tissue Viability 31(3): 523-30
77. Veličković VM, Lembelembe JP, Cegri F et al (2023) Superabsorbent Wound Dressing for Management of Patients With Moderate-to-Highly Exuding Chronic Leg Ulcers: An Early Stage Model-Based Benefit-Harm Assessment. Int J Low Extrem Wounds 22(2): 345-52
78. Veličković V M, Macmillan T, Lones E (2024) Systematic review and quality assessment of clinical and economic evidence for superabsorbent wound dressings in a population with chronic ulcers. Int Wound J 21(3): e14750
79. Walker M (2022) Human skin through the ages. Int J Pharm 622: 121850
80. Wang D, Liu C, Zhang X (2020) Do Physicians’ Attitudes towards Patient-Centered Communication Promote Physicians’ Intention and Behavior of Involving Patients in Medical Decisions? Int J Environ Res Public Health 17(17): 6393
81. World Health Organization (2025) Health workforce. Available at: https://www.who.int/health-topics/health-workforce#tab=tab_1 (accessed 25.1.2025)
82. Wounds International (2019) Wound exudate. Effective assessment and management. Wounds International, London. Available to download from www. woundsinternational.com
83. Wounds International (2023) Wound Balance: achieving wound healing with confidence. Wounds International, London. Available to download from www. woundsinternational.com
84. Wounds International (2024) Surgical wound dehiscence (SWD): International consensus statement on assessment, diagnosis and management. Wounds International, London. Available to download from www.woundsinternational.com
85. Zhu X, Olsson MM, Bajpai R (2022) Health-related quality of life and chronic wound characteristics among patients with chronic wounds treated in primary care: A cross-sectional study in Singapore. Int Wound J 19(5): 1121-32
Рецензия
Для цитирования:
Внедрение концепции раневого баланса: результаты и рекомендации на будущее. Раны и раневые инфекции. Журнал имени проф. Б.М. Костючёнка. 2025;12(3):6-59.
For citation:
Implementing Wound Balance: Outcomes and future recommendations. Wounds and wound infections. The prof. B.M. Kostyuchenok journal. 2025;12(3):6-59.
JATS XML























