ririРаны и раневые инфекции. Журнал имени проф. Б.М. КостючёнкаWounds and wound infections. The prof. B.M. Kostyuchenok journal2408-96132500-0594Regional non-governmental organization “Surgical society - Wounds and wound infections”10.17650/2408-9613-2016-3-2-19-23riri-87Research ArticleОБЗОРЫ, ЛЕКЦИИ, ИСТОРИЯ РАН И РАНЕВЫХ ИНФЕКЦИЙREVIEWS, LECTURES, HISTORY OF WOUNDS AND WOUND INFECTIONSБиологические маркеры в диагностике и лечении сепсиса (обзор литературы)Biological marker medications in the diagnosis and treatment of sepsis (literature review)ЗвягинА. А.ZvyaginA. A.

117997, Москва, ул. Большая Серпуховская, 27

27 Bol’shaya Serpukhovskaya St., Moscow, 117997

zvyagin@ixv.ruДемидоваВ. С.DemidovaV. S.

117997, Москва, ул. Большая Серпуховская, 27

27 Bol’shaya Serpukhovskaya St., Moscow, 117997

СмирновГ. В.SmirnovG. V.

117997, Москва, ул. Большая Серпуховская, 27

27 Bol’shaya Serpukhovskaya St., Moscow, 117997

ФГБУ «Институт хирургии им. А. В. Вишневского» Минздрава РоссииРоссияA. V. Vishnevsky Institute of Surgery, Ministry of Health of RussiaRussian Federation201608122016321923Copyright © Звягин А.А., Демидова В.С., Смирнов Г.В., 20162016Звягин А.А., Демидова В.С., Смирнов Г.В.Zvyagin A.A., Demidova V.S., Smirnov G.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.riri.su/jour/article/view/87

В статье представлен обзор литературы последних лет по проблеме ранней диагностики и эффективности лечения сепсиса, вызванного хирургической инфекцией. Показаны роль и значение раннего определения уровней биологических маркеров синдрома системной воспалительной реакции и сепсиса (С-реактивный белок, интерлейкин-6, прокальцитонин, пресепсин, neutrophil CD64), динамики их изменений в процессе лечения, чувствительность и специфичность.

The article gives a general review of the recent literature on the problem of early diagnosis and effective treatment of sepsis caused by surgical infection. It is overviewed the role and importance of early detection of biological markers of systemic inflammation response syndrome and sepsis (C-reactive protein, interleukin-6, procalcitonin, presepsin, neutrophil CD64), the dynamics of their changes in the process of treatment, their sensitivity and specificity.

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The authors declare that there are no conflicts of interest present.