ririРаны и раневые инфекции. Журнал имени проф. Б.М. КостючёнкаWounds and wound infections. The prof. B.M. Kostyuchenok journal2408-96132500-0594Regional non-governmental organization “Surgical society - Wounds and wound infections”10.25199/2408-9613-2021-8-2-28-32riri-246Research ArticleОБЗОРЫ, ЛЕКЦИИ, ИСТОРИЯ РАН И РАНЕВЫХ ИНФЕКЦИЙREVIEWS, LECTURES, HISTORY OF WOUNDS AND WOUND INFECTIONSИспользование шовного материала с триклозановым покрытием как профилактика инфекций области хирургического вмешательства (обзор литературы)Use of triclosan-coated suture material as prevention of surgical site infections (literature review)ШарковС. М.SharkovS. M.

Сергей Михайлович Шарков, Россия, 119049, Москва, 4-й Добрынинский пер., д. 1/9; Россия, 119991, Москва, ул. Большая Пироговская, д. 2, стр. 4

1/9 4th Dobryninsky per., Moscow, 119049, Russia; 2/4 Bolshaya Pirogovskaya Str., Moscow, 119991, Russia

Sharkdoc@mail.ruИхсановаС. Р.IkhsanovaS. R.

Россия, 119991, Москва, ул. Большая Пироговская, д. 2, стр. 4

2/4 Bolshaya Pirogovskaya Str., Moscow, 119991, Russia

ГБУЗ «Морозовская детская городская клиническая больница ДЗМ»; ФГАОУ ВО «Первый МГМУ имени И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияState Budgetary Healthcare Institution “Morozovskaya Children’s City Clinical Hospital HD of M”; Federal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University”, Ministry of Health of Russia (Sechenov University)Russian FederationФГАОУ ВО «Первый МГМУ имени И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияFederal State Autonomous Educational Institution of Higher Education “I.M. Sechenov First Moscow State Medical University”, Ministry of Health of Russia (Sechenov University)Russian Federation202101102021822832Copyright © Шарков С.М., Ихсанова С.Р., 20212021Шарков С.М., Ихсанова С.Р.Sharkov S.M., Ikhsanova S.R.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.riri.su/jour/article/view/246

По международным данным, частота развития инфекций области хирургического вмешательства у детей и взрослых варьирует от 2,0 до 20,0 %. На возникновение этих инфекций влияет множество факторов: наличие сопутствующих заболеваний, индекс ASA, класс хирургической раны, индекс риска NNIS, а также качество шовного материала. По оценкам специалистов Всемирной организации здравоохранения, 40,0–60,0 % инфекций области хирургического вмешательства можно предотвратить. Первое микробиологическое исследование шовного материала (полиглактин 910) с триклозаном было опубликовано в 2002 г. По данным международных исследований, использование триклозана снижает адгезию бактерий к шовному материалу, а также жизнеспособность микробов и высвобождение медиаторов воспаления. Триклозан активно препятствует колонизации нити. Кроме того, в течение длительного времени в окружающей среде поддерживаются концентрации, достаточные для подавления роста и размножения патогенов, следствием чего становится предупреждение развития инфекционных осложнений.

According to international data, the incidence of infections in the field of surgery in children and adults varies from 2.0 to 20.0 %. The occurrence of the above infections is influenced by many factors: the presence of comorbidities, ASA index, surgical wound class, NNIS risk index. Important factors include the quality of the suture. According to experts of the World Health Organization, 40.0–60.0 % of infections in the field of surgery can be prevented. The first microbiological study of suture (polyglactin 910) with triclosan was published in 2002. According to international studies, the use of a triclosan reduces the adhesion of bacteria to the suture, the viability of microbes and the release of inflammatory mediators. Triclosan actively prevents the colonization of the filament, in addition, concentrations sufficient to suppress the growth and reproduction of pathogens are maintained in the environment for a long time, resulting in the prevention of the development of infectious complications.

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The authors declare that there are no conflicts of interest present.