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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">riri</journal-id><journal-title-group><journal-title xml:lang="ru">Раны и раневые инфекции. Журнал имени проф. Б.М. Костючёнка</journal-title><trans-title-group xml:lang="en"><trans-title>Wounds and wound infections. The prof. B.M. Kostyuchenok journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2408-9613</issn><issn pub-type="epub">2500-0594</issn><publisher><publisher-name>Regional non-governmental organization “Surgical society - Wounds and wound infections”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25199/2408-9613-2019-6-2-44-59</article-id><article-id custom-type="elpub" pub-id-type="custom">riri-182</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Осложнения тромбоза глубоких вен: тромбоэмболия легочной артерии и венозная гангрена нижних конечностей (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Complications of deep vein thrombosis: pulmonary thromboembolism and venous gangrene of the lower extremities (clinical case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оруджева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Orudzheva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><email xlink:type="simple">osaida@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митиш</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitish</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ушаков</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Magomedova</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магомедова</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ushakov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блатун</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Blatun</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пасхалова</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Paskhalova</surname><given-names>Yu. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россия, 119997, г. Москва, ул. Бол. Серпуховская, 27</p></bio><bio xml:lang="en"><p>27, Bol’shaya Serpukhivskaya Str., Moscow, 117997, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ «НМИЦ хирургии им. А. В. Вишневского» Минздрава России<country>Россия</country></aff><aff xml:lang="en">FSGI “A.V. Vishnevsky National Medical Research Center of Surgery” Ministry of Health of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2019</year></pub-date><volume>6</volume><issue>2</issue><fpage>44</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Оруджева С.А., Митиш В.А., Ушаков А.А., Магомедова С.Д., Блатун Л.А., Пасхалова Ю.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Оруджева С.А., Митиш В.А., Ушаков А.А., Магомедова С.Д., Блатун Л.А., Пасхалова Ю.С.</copyright-holder><copyright-holder xml:lang="en">Orudzheva S.A., Mitish V.A., Magomedova S.D., Ushakov A.A., Blatun L.A., Paskhalova Y.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.riri.su/jour/article/view/182">https://www.riri.su/jour/article/view/182</self-uri><abstract><p>Венозные тромбозы и тромбоэмболические осложнения являются актуальной проблемой здравоохранения. Согласно современным рекомендациям по диагностике, лечению и профилактике венозных тромбоэмболических осложнений, пациенты стратифицированы по риску развития тромбоэмболии легочной артерии (ТЭЛА), по риску смерти при ТЭЛА, соответственно рекомендована диагностическая и лечебная тактика. Приверженность рекомендациям позволяет уменьшить летальность от ТЭЛА, в противном случае летальность от ТЭЛА остается высокой из-за проблем быстрой диагностики и адаптированной к риску терапии. Если ТЭЛА – это частое осложнение тромбоза глубоких вен (ТГВ), то венозная гангрена – довольно редкое, однако также ассоциированное с высокой летальностью. В статье приведено редкое клиническое наблюдение сочетания сразу двух тяжелых осложнений ТГВ: ТЭЛА и венозной гангрены обеих нижних конечностей. Несвоевременная диагностика и запоздалое лечение привели к ампутации обеих нижних конечностей, выполненной при наличии флотирующего тромба в нижней полой вене и правых отделах сердца. Анализируются причины несвоевременной диагностики и сложность разработки индивидуальной стратегии лечения одновременно развившихся осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Venous thrombosis and thromboembolic complications are an important public health problem. According to current recommendations for the diagnosis, treatment and prevention of venous thromboembolic complications, patients are stratified by the risk of pulmonary embolism, by the risk of death in pulmonary embolism, respectively, diagnostic and therapeutic tactics are recommended. Adherence to the recommendations allows to reduce mortality from pulmonary embolism, in the opposite case, mortality from pulmonary embolism remains high due to the problems of rapid diagnosis and risk-adjusted therapy. If pulmonary embolism is a frequent complication of venous thrombosis, then venous gangrene is a rather rare complication, which is also characterized by high mortality. A rare case of a combination of two serious complications of deep vein thrombosis is described: thromboembolism of the pulmonary artery and venous gangrene of both lower extremities. Late diagnosis and late treatment led to amputation of both lower extremities, performed in the presence of a floating thrombus in the inferior vena cava and right heart. The causes of late diagnosis and the complexity of the treatment of simultaneously developed two complications are analyzed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбоз глубоких вен</kwd><kwd>венозная гангрена</kwd><kwd>тромбоэмболия легочной артерии</kwd><kwd>проводниковая анестезия</kwd><kwd>ампутация нижней конечности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>deep vein thrombosis</kwd><kwd>venous gangrene</kwd><kwd>pulmonary thromboembolism</kwd><kwd>conduction anesthesia</kwd><kwd>amputation of the lower limb</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Access Economics. The burden of venous thromboembolism in Australia. Report for the Australia and New Zealand Working Party on the Management and Prevention of Venous Thromboembolism 2008;49.</mixed-citation><mixed-citation xml:lang="en">Access Economics. 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